There are a number of papers on clinical utility, including one by Felix Frueh and myself in 2014 (pubmed here, journal here) which is not open access, although my own explanation of it is (here). The most comprehensive review article on clinical utility is Parkinson et al., here.
See also the 2014 article, "New Thinking on Clinical Utility: Hard Lessons for Molecular Diagnostics," online at the influential Amer J Managed Care and open access, here.